Chronic Wound Management: Complete Guide to Treatment & Care

Medically reviewed by Dr. Amal Obaid-Schmid, MD | Board-Certified Physician, 18 years acute care experience, Former Trauma Medical Director

Table of Contents

When a wound refuses to heal despite weeks of careful care, frustration and worry naturally follow. You’ve changed dressings, kept the area clean, and done everything right—yet the wound persists. You’re not alone. Chronic wounds affect over 10.5 million Medicare beneficiaries in the United States, representing 16.3% of all recipients.(1) These wounds cause physical discomfort while impacting your quality of life, mobility, and emotional well-being.

Chronic wound management requires a comprehensive approach addressing both the wound itself and the underlying factors preventing healing. Whether you’re dealing with a diabetic foot ulcer, pressure sore, or venous leg ulcer, understanding what makes wounds chronic and how modern treatments can help is your first step toward healing. At Elite Rapid Care in Henderson, Nevada, we specialize in advanced wound care combining cutting-edge treatments like hyperbaric oxygen therapy with the accessibility and convenience of urgent care.

This guide will help you understand chronic wounds, recognize when professional care is necessary, and discover treatment options that can finally help your wound heal.

Understanding Chronic Wounds

What Qualifies as a Chronic Wound?

A chronic wound is any wound that fails to heal within the expected timeframe—typically four to twelve weeks—despite appropriate treatment.(2) Unlike acute wounds that progress smoothly through normal healing stages, chronic wounds become “stuck” in one phase, usually inflammation, preventing normal tissue repair.

The annual cost of treating chronic wounds in the United States exceeds $28 billion for Medicare alone, with additional billions in lost productivity and reduced quality of life.(1) These wounds can lead to serious complications including infection, amputation, and in severe cases, life-threatening sepsis.

Several types of wounds commonly become chronic:

  • Diabetic foot ulcers affecting the feet and lower legs
  • Pressure ulcers (bedsores) developing over bony prominences
  • Venous leg ulcers caused by poor circulation in the veins
  • Arterial ulcers resulting from inadequate blood supply
  • Surgical wounds that fail to heal properly

Understanding what you’re dealing with helps you seek appropriate care before complications develop.

Why Chronic Wounds Don’t Heal

Normal wound healing progresses through three overlapping phases: inflammation (cleaning the wound), proliferation (building new tissue), and remodeling (strengthening the healed tissue).(3) When chronic wounds get stuck, it’s usually because something interferes with this natural progression.

Underlying health conditions are the most common culprits:

  • Diabetes damages nerves and blood vessels, reducing circulation and sensation
  • Vascular disease limits oxygen and nutrients reaching the wound
  • Immune system disorders impair the body’s ability to fight infection and rebuild tissue
  • Malnutrition deprives the body of protein and vitamins essential for healing
  • Chronic inflammation keeps wounds in a destructive cycle

Local wound factors also prevent healing:

  • Persistent infection or biofilm formation
  • Repeated trauma or pressure to the area
  • Excessive fluid (too wet) or dryness (too dry)
  • Poor tissue oxygenation

In Nevada, where 11% of adults live with diabetes—approximately 269,783 people—understanding these risk factors is particularly important for our Henderson community.(4)

The Chronic Wound Healing Process

Medical professionals use the TIME principle as a framework for effective chronic wound management:(5)

T – Tissue Management: Removing dead tissue (debridement) to expose healthy tissue.

I – Infection and Inflammation Control: Treating bacterial biofilms and managing excessive inflammation.

M – Moisture Balance: Maintaining optimal moisture with appropriate dressings.

E – Edge Advancement: Ensuring wound edges actively migrate toward the center.

This systematic approach addresses each barrier to healing.

Wound healing process and TIME principle

Types of Chronic Wounds

Diabetic Foot Ulcers: Causes, Symptoms, and Treatment

If you have diabetes, your lifetime risk of developing a foot ulcer is approximately 25%.(6) These wounds develop from minor injuries you might not feel due to neuropathy (nerve damage), combined with poor circulation and immune system impairment.

Studies show 31% of diabetic foot ulcers lead to amputation when not properly managed,(6) but aggressive wound care dramatically improves outcomes.

Warning signs: Open sore lasting more than a few days, drainage, foul odor, redness extending beyond wound edges, warm skin, swelling, or increasing pain.

Treatment: Offloading with special shoes or boots, regular debridement, infection management, and maintaining HbA1c below 7%. Advanced treatments at Elite Rapid Care include HBOT, Wound VAC, and bioengineered skin substitutes.

Pressure Ulcers (Bedsores): Stages and Care

Pressure ulcers affect approximately 2.5 million Americans annually.(8) These wounds develop when sustained pressure reduces blood flow to skin and tissue. High-risk individuals include bedridden or wheelchair-bound patients, those with reduced sensation, poor nutrition, or fragile skin.

The National Pressure Injury Advisory Panel stages injuries from Stage 1 (non-blanchable redness) through Stage 4 (full-thickness loss with exposed bone/tendon/muscle).(9)

Treatment: Early-stage ulcers need immediate pressure relief, repositioning every 2 hours, pressure-redistributing surfaces, and appropriate dressings. Advanced ulcers require professional assessment, surgical debridement, and possible repair.

Caregiver prevention: Reposition every 2 hours, check skin daily over bony areas, maintain nutrition and hydration, keep skin clean and moisturized, and use pressure-redistributing surfaces.

Venous Leg Ulcers: Understanding and Management

Venous leg ulcers account for approximately 70% of all leg ulcers,(10) developing when damaged vein valves cause blood pooling and tissue breakdown. These wounds typically appear on the inner ankle or lower calf with shallow, irregular borders and moderate to heavy drainage, plus leg swelling and aching.

Treatment: Compression therapy is cornerstone treatment, with 40-70% healing rates at 12 weeks.(11) Treatment includes multi-layer bandaging or compression stockings (20-30 mmHg), leg elevation above heart level several times daily, regular walking to activate calf muscles, and appropriate dressings.

Important: Never apply compression if arterial disease is present. Professional evaluation is essential.

Preventing recurrence: Venous ulcers have a 50% recurrence rate within 12 months without ongoing management.(10) Continue lifelong compression stockings, daily leg elevation, regular exercise, and address underlying vein problems.

Arterial Ulcers and Other Chronic Wound Types

Arterial ulcers develop when blocked arteries limit blood flow to tissues. These wounds differ from venous ulcers—they appear on feet, toes, or heels with a “punched out” appearance, are extremely painful (especially at night), and have minimal drainage. Treatment focuses on restoring blood flow through vascular surgery or angioplasty, as wounds won’t heal without adequate circulation.

Other chronic wound types include surgical wounds that fail to close post-operatively, traumatic wounds from accidents that become chronic, and radiation wounds from cancer therapy.

Signs and Symptoms: When Your Wound Needs Attention

Warning Signs of Wound Infection

Wound infection transforms a manageable situation into a medical emergency. Learn to recognize these warning signs:

Local infection indicators:

  • Increasing pain or tenderness around the wound
  • Expanding redness spreading beyond wound edges
  • Warmth or heat radiating from the wound site
  • Purulent drainage (thick, yellow, green, or brown discharge)
  • Foul odor that persists after cleaning
  • Wound size increasing rather than decreasing

Systemic infection signs (these indicate infection has spread):

  • Fever above 100.4°F (38°C)
  • Chills or sweating
  • Rapid heart rate
  • Confusion or disorientation (especially in elderly patients)
  • Red streaking extending from the wound (lymphangitis)

Biofilm formation:

Biofilm—organized bacterial communities that resist immune attacks and antibiotics—affects over 90% of chronic wounds.(12) Signs include clean-appearing wounds that won’t heal, recurring infection despite treatment, and slimy or shiny wound appearance.

Complications of Untreated Chronic Wounds

Ignoring a chronic wound or delaying treatment invites serious complications:

Cellulitis: Bacterial infection of deeper skin layers causes rapidly spreading redness, warmth, swelling, and pain.

Osteomyelitis: Bone infection affects approximately 20% of diabetic foot ulcers and can necessitate amputation if not treated aggressively.(13)

Sepsis: When infection enters the bloodstream, it triggers a life-threatening inflammatory response affecting multiple organ systems.

Amputation: Particularly with diabetic foot ulcers, the amputation rate reaches 31% when wounds aren’t properly managed.(6)

Quality of life impacts include chronic pain, mobility limitations, wound odor causing social embarrassment, and anxiety about complications. These consequences underscore why early, aggressive wound management is so important.

Chronic Wound Treatment Options

Standard Wound Care Approaches

Effective chronic wound management starts with comprehensive assessment followed by systematic treatment.

Wound assessment and debridement:

Treatment begins with thorough evaluation of wound characteristics, vascular status, and underlying conditions. Removing dead tissue through sharp, enzymatic, or autolytic debridement is essential for healing.(14)

Dressing selection and moisture balance:

Modern dressings create optimal healing environments: hydrogels for dry wounds, foam for moderate drainage, alginates for heavy drainage, and antimicrobial dressings for infection control. Research shows wounds heal 50% faster in moist environments.(15)

Nutrition for healing:

Your body needs building blocks to repair tissue. Increase protein to 1.25-1.5 g/kg body weight daily, consume 500-1000 mg vitamin C, ensure adequate zinc (15-20 mg daily), and stay well-hydrated.(16)

Offloading:

For foot ulcers and pressure injuries, eliminating pressure is non-negotiable. Proper offloading improves diabetic foot ulcer healing rates from 30% to over 90%.(17)

Advanced Wound Care Technologies

When standard treatments plateau or wounds involve complex factors, advanced therapies can provide the breakthrough needed for healing.

Hyperbaric Oxygen Therapy (HBOT) for Chronic Wounds

Hyperbaric oxygen therapy involves breathing 100% oxygen in a pressurized chamber at 2-3 times normal atmospheric pressure.(18) This saturates plasma with oxygen, reaching areas with impaired circulation, stimulating blood vessel formation, and enhancing bacterial killing.

The FDA has approved HBOT for diabetic foot ulcers unresponsive to conventional treatment. Clinical studies demonstrate a 40% absolute increase in healing rates.(19)

Treatment involves 90-120 minute sessions, 20-40 total treatments over 4-8 weeks. Patients can watch TV or rest during sessions. Side effects are minor: temporary vision changes, ear pressure, mild fatigue.

Elite Rapid Care offers on-site HBOT in Henderson, making advanced treatment accessible without hospital referrals or long waits.

Negative Pressure Wound Therapy (Wound VAC)

Negative pressure wound therapy (NPWT), commonly called “Wound VAC,” applies controlled suction through specialized dressings connected to a portable pump.(20) This removes excess fluid, reduces edema, increases blood flow, promotes granulation tissue formation, and draws wound edges together.

When is Wound VAC recommended?

This therapy works particularly well for large deep wounds, surgical wounds that separate, diabetic foot ulcers, and Stage 3-4 pressure ulcers.

Effectiveness data:

Research demonstrates that NPWT reduces wound volume 50% faster than conventional dressings while decreasing infection rates.(21) Modern systems are portable, battery-operated, and relatively quiet.

Elite Rapid Care provides negative pressure wound therapy with proper patient education, regular monitoring, and timely dressing changes.

Bioengineered Skin Substitutes and Growth Factors

When wounds lack cellular components needed for healing, bioengineered products (Dermagraft, Apligraf, AlloDerm) or growth factors (Becaplermin gel) provide missing elements. These are typically reserved for wounds failing standard therapy when adequate blood supply exists and infection is controlled.

Medications and Infection Management

Systemic antibiotics treat infections extending beyond the wound surface, with selection based on suspected bacteria and severity.

Topical antimicrobials (silver sulfadiazine, iodine products, medical-grade honey) treat surface colonization without systemic effects.

Pain management is essential. Adequate pain control promotes healing by reducing stress hormones that interfere with tissue repair.(22)

Home Care and Prevention Strategies

Daily Wound Care for Patients and Caregivers

Proper home wound care technique significantly affects healing outcomes.

Step-by-step approach:

  1. Wash hands thoroughly and gather supplies (gloves, saline, prescribed dressings, tape)
  2. Remove old dressing gently (moisten if stuck)
  3. Clean wound with saline and pat dry
  4. Assess for size changes, drainage, odor, and infection signs
  5. Apply prescribed treatment and fresh dressing with adequate coverage
  6. Secure dressing appropriately and document changes

Contact your provider for:

  • Infection signs (increasing redness, swelling, warmth, purulent drainage, fever)
  • Increased pain or wound enlargement
  • New skin breakdown or uncontrolled bleeding

Prevention by Wound Type

Preventing diabetic foot ulcers:
Inspect feet daily, wash and dry carefully, moisturize (not between toes), trim nails straight across, always wear shoes, check inside shoes before wearing, control blood sugar (HbA1c below 7%), and get annual foot exams.

Preventing pressure ulcers:
Reposition every 2 hours, inspect skin twice daily at pressure points, use pressure-redistributing surfaces, keep skin clean and dry, optimize nutrition, and minimize friction during repositioning.

Preventing venous leg ulcers:
Wear compression stockings daily (20-30 mmHg), elevate legs above heart 30 minutes three times daily, exercise daily to activate calf muscles, maintain healthy weight, and avoid prolonged standing or sitting.

Managing Underlying Conditions

Your overall health directly affects wound healing.

Blood sugar control is critical for people with diabetes. High blood sugar impairs white blood cell function and promotes inflammation.(23) Work with your diabetes care team to monitor consistently.

Circulation improvement: Stop smoking (the single most important factor for wound healing),(24) exercise regularly, manage blood pressure and cholesterol, and consider vascular evaluation if wounds aren’t healing.

Nutritional optimization: Eat protein at every meal, choose nutrient-dense foods, stay well-hydrated, and consider high-protein supplements if needed.

Desert Climate Considerations for Wound Healing

Nevada’s desert climate presents unique challenges for wound healing.

Hydration: Arid climate causes rapid fluid loss, impairing healing. Drink 8-10 glasses of water daily and monitor urine color (pale yellow indicates good hydration).

Dry air: Low humidity (10-30%) dries wound beds quickly. Use humidifiers (maintain 40-50% humidity), apply prescribed moisturizers to surrounding skin, and consider occlusive dressings.

Sun protection: Intense UV damages healing tissue. Cover wounds outdoors, use broad-spectrum SPF 30+ sunscreen on surrounding skin, wear protective clothing, and continue sun protection for 6 months after healing.

Heat management: Triple-digit summer temperatures stress the body. Stay indoors during extreme heat and use air conditioning.

When to Seek Professional Wound Care

Signs You Need Immediate Medical Attention

Some wound complications require emergency room evaluation. Go to the ER immediately if you experience:

  • Fever above 103°F (39.4°C) or any fever with confusion
  • Red streaking extending rapidly from the wound
  • Rapidly spreading redness advancing more than an inch per hour
  • Signs of sepsis: Extreme weakness, confusion, rapid breathing, racing heart
  • Uncontrolled bleeding that doesn’t stop with pressure
  • Severe pain disproportionate to the wound
  • Skin that feels hard or woody (possible necrotizing infection)

Don’t second-guess yourself with these symptoms. Emergency conditions require immediate intervention.

When to Visit Urgent Care for Wound Treatment

Many chronic wound situations benefit from prompt attention but don’t require ER-level care. Elite Rapid Care offers walk-in chronic wound care in Henderson with no appointment necessary.

Visit urgent care when:

  • Wound present for more than 4 weeks without improvement
  • Infection signs develop (increasing redness, warmth, swelling, purulent drainage, fever below 103°F)
  • Pain worsening or drainage increases/changes
  • Current wound care routine isn’t working
  • You need wound cultures or professional debridement

Urgent care advantages: Unlike hospital-based wound centers requiring referrals and 2-4 week waits, Elite Rapid Care provides walk-in access with no referral, immediate assessment, on-site diagnostics (lab testing, wound cultures, X-rays), same-day treatment initiation, extended hours, and wide insurance acceptance.

What to bring: List of current medications, previous wound measurements or photos, treatments already tried, and insurance information.

Our board-certified physicians combine evidence-based wound care with advanced technologies like HBOT and Wound VAC in an accessible urgent care setting.

When to See a Wound Care Specialist

Some complex situations benefit from specialized wound care expertise. Consider specialist referral when wounds require highly specialized surgical reconstruction, fail to improve after 12 weeks of appropriate care, or involve complex systemic conditions requiring multidisciplinary coordination.

Elite Rapid Care maintains relationships with excellent wound care specialists throughout Henderson and Las Vegas. When specialist referral is appropriate, we’ll coordinate the transition while continuing to provide accessible care for other health needs.

Elite Rapid Care’s Approach to Chronic Wounds

At Elite Rapid Care, advanced wound care doesn’t require months of waiting or complex referral systems. Our comprehensive chronic wound management combines:

  • Comprehensive assessment using standardized techniques
  • Evidence-based treatment planning with TIME principle
  • Access to advanced technologies (HBOT, Wound VAC, bioengineered products)
  • Coordinated multidisciplinary care when needed
  • Patient and caregiver education
  • Extended hours (Wed-Mon 8am-8pm, Tue 8am-4pm)

Our Henderson location at 2960 Sunridge Heights Parkway serves residents throughout Henderson, Las Vegas, and greater Clark County.

If you’re concerned about a chronic wound, don’t wait. Walk in anytime or call (725) 291-5900. Early intervention dramatically improves outcomes.

Learn more about our comprehensive wound care services

Frequently Asked Questions About Chronic Wounds

What qualifies as a chronic wound?

A chronic wound is any wound that fails to heal within the expected timeframe of 4 to 12 weeks despite appropriate treatment. These wounds get stuck in one phase of healing, usually inflammation, preventing normal tissue repair and closure. Common types include diabetic foot ulcers, pressure ulcers, and venous leg ulcers.

How long does a chronic wound take to heal?

Healing time varies by wound type. Diabetic foot ulcers typically require 12-20 weeks with standard care (advanced treatments like HBOT accelerate healing). Pressure ulcers may heal in 8-12 weeks for Stage 2-3 wounds with proper pressure relief. Venous leg ulcers often take 6-12 months.

Why don’t chronic wounds heal?

Chronic wounds fail to heal due to underlying conditions disrupting normal healing. Diabetes damages blood vessels and nerves, reducing circulation and sensation. Vascular disease limits oxygen delivery. Persistent infection or biofilm maintains inflammation. Malnutrition, advanced age, and medications also prevent normal healing.

Should wounds be kept moist or dry?

Research shows wounds heal 50% faster in moist environments. Moisture allows cell migration, enzyme function, and growth factor activity. However, excessive moisture causes maceration. The goal is balanced moisture using appropriate modern dressings.

What is the TIME principle in wound care?

TIME is a systematic framework: Tissue management (debriding dead tissue), Infection/inflammation control, Moisture balance, and Edge advancement. This approach addresses all common barriers to healing.

When should I seek medical attention for a wound?

Seek emergency care for high fever with confusion, rapidly spreading redness, severe pain, sepsis signs, or uncontrolled bleeding. Visit urgent care for wounds not healing after 4 weeks, infection signs (increasing redness, warmth, purulent drainage, fever below 103°F), or worsening pain. Early intervention prevents complications.

Can chronic wounds be cured?

Most chronic wounds heal with appropriate treatment. Diabetic foot ulcers heal in 60-90% of cases with aggressive care and blood sugar control. Venous leg ulcers heal with compression therapy but recur in 50% without continued compression. Success requires treating both wound and underlying conditions.

What are the treatment options for chronic wounds?

Treatment begins with assessment, debridement, dressing selection, infection management, and addressing underlying conditions. Advanced options include hyperbaric oxygen therapy (HBOT), negative pressure wound therapy (Wound VAC), bioengineered skin substitutes, and growth factor applications when standard care plateaus.

Does insurance cover advanced wound treatments?

Medicare and most major insurers cover medically necessary advanced treatments including HBOT and Wound VAC when specific criteria are met—typically requiring documentation that standard care has failed. At Elite Rapid Care, we work with insurance companies to determine coverage and handle authorizations.

How can I prevent chronic wounds from recurring?

Prevention depends on wound type. Diabetic foot ulcers: inspect feet daily, wear appropriate footwear, control blood sugar, get regular foot exams. Pressure ulcers: reposition every 2 hours, use pressure-redistributing surfaces, maintain nutrition, inspect skin twice daily. Venous leg ulcers: wear 20-30 mmHg compression stockings daily, elevate legs regularly, exercise daily, treat underlying venous disease.

Conclusion: Taking Control of Your Wound Healing Journey

Chronic wounds can feel overwhelming, but understanding the healing process and your treatment options empowers you to take control. This comprehensive guide to chronic wound management has covered wound types, treatment approaches, and prevention strategies. Whether you’re dealing with a diabetic foot ulcer, pressure sore, or venous leg ulcer, healing is possible with the right approach.

Key takeaways:

  • Chronic wounds require professional assessment to identify underlying causes
  • Standard care focuses on debridement, infection control, moisture balance, and systemic factors
  • Advanced treatments like HBOT and Wound VAC provide breakthroughs when standard care plateaus
  • Prevention strategies reduce recurrence risk
  • Early intervention dramatically improves outcomes

Don’t accept “it’s just not healing” as an answer. At Elite Rapid Care, we’ve made advanced wound care accessible to the Henderson community without referrals, long waits, or limited scheduling.

If you’re concerned about a chronic wound, our experienced team offers comprehensive assessment, evidence-based treatment, and access to advanced therapies.

Visit Elite Rapid Care at 2960 Sunridge Heights Parkway, Suite 100, Henderson, NV 89052
Call: (725) 291-5900
Hours: Wed-Mon 8am-8pm | Tue 8am-4pm

Schedule an appointment or walk in anytime. Your healing journey starts with that first step.

References

  1. Nussbaum SR, Carter MJ, Fife CE, et al. An economic evaluation of the impact, cost, and Medicare policy implications of chronic nonhealing wounds. Value Health. 2018;21(1):27-32. doi:10.1016/j.jval.2017.07.007
  2. Frykberg RG, Banks J. Challenges in the treatment of chronic wounds. Adv Wound Care (New Rochelle). 2015;4(9):560-582. doi:10.1089/wound.2015.0635
  3. Guo S, DiPietro LA. Factors affecting wound healing. J Dent Res. 2010;89(3):219-229. doi:10.1177/0022034509359125
  4. Centers for Disease Control and Prevention. National Diabetes Statistics Report. Published 2024. Accessed October 2025. https://www.cdc.gov/diabetes/data/statistics-report/
  5. Schultz GS, Sibbald RG, Falanga V, et al. Wound bed preparation: a systematic approach to wound management. Wound Repair Regen. 2003;11(Suppl 1):S1-S28. doi:10.1046/j.1524-475X.11.s2.1.x
  6. Armstrong DG, Boulton AJM, Bus SA. Diabetic foot ulcers and their recurrence. N Engl J Med. 2017;376(24):2367-2375. doi:10.1056/NEJMra1615439
  7. Wagner FW Jr. The dysvascular foot: a system for diagnosis and treatment. Foot Ankle. 1981;2(2):64-122. doi:10.1177/107110078100200202
  8. Padula WV, Delaramente BA. The national cost of hospital-acquired pressure injuries in the United States. Int Wound J. 2019;16(3):634-640. doi:10.1111/iwj.13071
  9. National Pressure Injury Advisory Panel. NPIAP pressure injury stages. Published 2016. Updated 2024. Accessed October 2025. https://npiap.com/page/PressureInjuryStages
  10. O’Donnell TF Jr, Passman MA, Marston WA, et al. Management of venous leg ulcers: clinical practice guidelines of the Society for Vascular Surgery and the American Venous Forum. J Vasc Surg. 2014;60(2 Suppl):3S-59S. doi:10.1016/j.jvs.2014.04.049
  11. O’Meara S, Cullum N, Nelson EA, Dumville JC. Compression for venous leg ulcers. Cochrane Database Syst Rev. 2012;11:CD000265. doi:10.1002/14651858.CD000265.pub3
  12. James GA, Swogger E, Wolcott R, et al. Biofilms in chronic wounds. Wound Repair Regen. 2008;16(1):37-44. doi:10.1111/j.1524-475X.2007.00321.x
  13. Lavery LA, Armstrong DG, Wunderlich RP, Mohler MJ, Wendel CS, Lipsky BA. Risk factors for foot infections in individuals with diabetes. Diabetes Care. 2006;29(6):1288-1293. doi:10.2337/dc05-2425
  14. Strohal R, Dissemond J, O’Brien JJ, et al. EWMA document: debridement. J Wound Care. 2013;22(Suppl 1):S1-S52. doi:10.12968/jowc.2013.22.Sup1.S1
  15. Winter GD. Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig. Nature. 1962;193:293-294. doi:10.1038/193293a0
  16. Arnold M, Barbul A. Nutrition and wound healing. Plast Reconstr Surg. 2006;117(7 Suppl):42S-58S. doi:10.1097/01.prs.0000225432.17501.6c
  17. Bus SA, Armstrong DG, Gooday C, et al. Guidelines on offloading foot ulcers in persons with diabetes (IWGDF 2023 update). Diabetes Metab Res Rev. 2024;40(3):e3647. doi:10.1002/dmrr.3647
  18. Thom SR. Hyperbaric oxygen: its mechanisms and efficacy. Plast Reconstr Surg. 2011;127(Suppl 1):131S-141S. doi:10.1097/PRS.0b013e3181fbe2bf
  19. Kranke P, Bennett MH, Martyn-St James M, Schnabel A, Debus SE, Weibel S. Hyperbaric oxygen therapy for chronic wounds. Cochrane Database Syst Rev. 2015;6:CD004123. doi:10.1002/14651858.CD004123.pub4
  20. Huang C, Leavitt T, Bayer LR, Orgill DP. Effect of negative pressure wound therapy on wound healing. Curr Probl Surg. 2014;51(7):301-331. doi:10.1067/j.cpsurg.2014.04.001
  21. Ubbink DT, Westerbos SJ, Nelson EA, Vermeulen H. A systematic review of topical negative pressure therapy for acute and chronic wounds. Br J Surg. 2008;95(6):685-692. doi:10.1002/bjs.6238
  22. Kiecolt-Glaser JK, Marucha PT, Mercado AM, Malarkey WB, Glaser R. Slowing of wound healing by psychological stress. Lancet. 1995;346(8984):1194-1196. doi:10.1016/s0140-6736(95)92899-5
  23. Baltzis D, Eleftheriadou I, Veves A. Pathogenesis and treatment of impaired wound healing in diabetes mellitus: new insights. Adv Ther. 2014;31(8):817-836. doi:10.1007/s12325-014-0140-x
  24. Sørensen LT. Wound healing and infection in surgery: the pathophysiological impact of smoking, smoking cessation, and nicotine replacement therapy. Ann Surg. 2012;255(6):1069-1079. doi:10.1097/SLA.0b013e31824f632d

Medical Disclaimer

This content is for educational and informational purposes only and does not constitute medical advice. Chronic wounds are serious medical conditions that require professional evaluation and treatment. The information provided here should not replace consultation with a qualified healthcare provider who can assess your individual situation, make diagnoses, and recommend appropriate treatment plans.

While we strive to provide accurate and current information, medical knowledge evolves continuously. Always consult with your healthcare provider before making decisions about your wound care or treatment options.

If you experience emergency symptoms including high fever, rapidly spreading redness, signs of sepsis, or uncontrolled bleeding, seek immediate emergency medical attention by calling 911 or going to the nearest emergency room.

Medically Reviewed by

Dr. Amal Obaid-Schmid, MD | Medical Director, Elite Rapid Care

Dr. Obaid-Schmid is a triple-boarded physician with 18 years of acute care experience, including 15 years as Trauma Medical Director at Huntington Hospital. She received both her MS in Microbiology & Molecular Genetics and MD from UCLA. Dr. Obaid-Schmid’s extensive experience in acute care and trauma medicine has given her deep expertise in complex wound management, infection control, and advanced treatment modalities.

This article was medically reviewed by Dr. Obaid-Schmid to ensure accuracy and adherence to current evidence-based wound care guidelines.

Learn more about Dr. Obaid-Schmid and Elite Rapid Care

Last Reviewed: October 27, 2025

Elite Rapid Care is committed to providing accurate, trustworthy health information to the Henderson, Las Vegas, and greater Clark County communities we serve. We review and update our content regularly to reflect the latest medical research and clinical guidelines.


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